Large numbers of individuals have developed an interest in liquid biopsy in recent years. This may not be a surprise, as the potential for clinical implications could be a result of the ability to detect and characterize malignancies in a modest and repeatable manner. It is unsurprising that extraordinary devices have been created to facilitate this endeavor.
However, clinical oncologists have not yet integrated the technique into their standard toolkit. It appears that the research community is losing focus on a variety of assays that are based on various principles, as there are so many things to focus on.
Regrettably, the two biomarkers detected by liquid biopsy, Circulating Tumor Cells (CTCs) and Circulating cell-free tumor DNA (ctDNA), are still susceptible to technical variability. This is primarily the case for pre-analytical and analytical steps.
Fortunately, initiatives are already underway to resolve these concerns, making sure that more clinicians worldwide have access to liquid biopsy. Nevertheless, this does not inherently imply that their primary objective is to identify and improve a distinctive liquid biopsy methodology.
The main focus is on determining the precise combination of indicators that indicate the status of a particular health complication, such as lung cancer or any other type, as well as its origin and progression. We must also keep a close check on the immune cells of the circulating microenvironment to make sure that the situation does not end at that point.
More interventional clinical trials are required to make liquid biopsies successful because researchers have known about their capabilities for some time now. However, how can this be achieved without sacrificing any of one’s principles?
It is at this juncture that policymakers within the industry must intervene. It will be straightforward and easy to implement sophisticated methods, creating a non-invasive, quick, and dependable decision-making tool that we can rely on at any time.
The future of liquid biopsy lung cancer appears to be promising as additional advancements are made. It is even more intriguing that clinicians in a variety of regions of the world are highly aware of liquid biopsy.
It is essential to obtain knowledge about the current situation in order to prevent oneself from being overtaken. It is fortunate that this is no longer a cause for concern once one has a comprehensive understanding of lung cancer and the corresponding diagnostic methods and treatments.
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